TWYNSTA® FOR HEALTHCARE PROFESSIONALS — Twynsta (telmisartan/amlodipine) Tablets are indicated for the treatment of hypertension, alone or with other antihypertensive agents. They may be used in patients whose blood pressure is not adequately controlled on antihypertensive monotherapy. TWYNSTA tablets may also be used as initial therapy in patients who are likely to need multiple drugs to achieve their blood pressure goals. Read full indication statement Twynsta Home Important Safety Information Prescribing Information Mechanism of Action — Twynsta® (telmisartan/amlodipine) Tablets — Mechanism of Action

TWYNSTA Mechanism of Action

Review the mechanism of action of TWYNSTA—A fixed-dose ARB/CCB combining telmisartan and amlodipine for the treatment of hypertension


Twynsta® (telmisartan/amlodipine) Tablets have been shown to be effective in lowering blood pressure. TWYNSTA is a combination of 2 drugs with antihypertensive properties: a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker [CCB])—amlodipine besylate—and an angiotensin II receptor blocker (ARB)—telmisartan.

Both telmisartan and amlodipine lower blood pressure by reducing peripheral resistance, but do so through complementary mechanisms.

Review telmisartan mechanism of action

Review amlodipine mechanism of action

TWYNSTA was studied in 1 placebo-controlled and 2 active-controlled trials.

Review study results

Visit the MICARDIS for Healthcare Professionals Web site to access tools and resources designed to help you create individualized treatment plans for your hypertensive patients.

Go to www.MicardisPro.com

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